Author(s): Maryam Montazeri, Mohammad Reza Ebadpour1, Farideh Kouchak, Naser Esmaeili
Common variable immune deficiency disease (CVID) is the most prevalent acquired immune deficiency in a human being after selective immunoglobulin A deficiency. It causes reduction of immunoglobulin levels and specific antibodies production and enhancement of recurrent and chronic infections risk, especially respiratory infections. The CVID patients face increased the risk of granulomatous disease, autoimmune and phenomenon, and malignancy. The disease involves males and females equally. Some studies showed that early diagnosis of CVID disease and conventional treatment of patients with intravenous immunoglobin might have an effective role in decreasing pneumonia and frequency of hospitalization due to infections and its complications. In this study, we report a 16 years old girl with CVID, without a clinical history of determined infection with recurrent sinusitis