Internal Medicine and Medical Investigation Journal

ISSN: 2474-7750

Correlation of Muscle Strength and Mass with Bone Mineral Density in Postmenopausal Women


Author(s): Veline Martínez, Harold Saavedra, Mayra Rojas, Juan José Martínez, Marisol Posada, Guillermo Guzmán

Osteoporosis is a systemic disease of the bone, which entails an increased risk

of fracture, with high impact on morbidity, mortality and costs in the health system. Several

studies have shown a relationship between muscle mass and strength with bone mineral density.

Our objective is to determine the correlation between these variables in postmenopausal


Materials and Methods:

For the correlation study, 100 postmenopausal women

older than 50 years were selected randomly and a sociodemographic survey was conducted,

and muscle strength was determined by manual grip strength, which was measured with a

digital dynamometer. Bone mineral density measurements and muscle mass were obtained

with densitometry. The correlation between strength, muscle mass, and bone mineral density

was determined by a Spearman correlation.


The average age was 62.8 ± 7.48. Femur

and column bone mineral density were significantly related to the muscle mass index, weight,

and body mass index. The prevalence of fragility fracture was 17%. The bone mineral density

of the femur was lower in patients with fragile fracture, and there was a negative and significant

correlation between femur bone mineral density and skeletal muscle mass index.


Bone health studies should include the study of muscle mass index and the skeletal muscle

mass index. The improvement of the muscle mass index can influence femoral and vertebral

bone mineral density with significant impact on fragility fractures. This is the first study of its

kind conducted in Colombia and South America.

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