Internal Medicine and Medical Investigation Journal

ISSN: 2474-7750

Evaluation of Antibacterial Activity of Essential Oil of Ziziphora clinopodioides and Achillea wilhelmsii on Antibiotic-resistant Strains of Staphylococcus aureus


Author(s): Abolfazl Jafari-Sales, Ahmadreza Shahniani, Reza Fathi, Parviz Malekzadeh, Haedeh Mobaiyen, Farnaz Rasi-Bonab

Background: The use of drugs to treat diseases led to the emergence of resistant strains of bacteria. Bacterial resistance to antibiotics is the most common problems in medical science. This study was aimed to evaluate the antimicrobial effects of essential oil of Ziziphora clinopodioides and Achillea wilhelmsii on against resistant clinical strains of Staphylococcus aureus. Methods: After collecting plants and validate its scientific name by botanists of Agricultural Organization and after drying in the shade, essential oil of Z. clinopodioides and A. wilhelmsii, extracted with steam distillation method by Clevenger and antimicrobial effects of essential oil by well diffusion on bacteria mentioned above were interpreted. The amount of essential oil were injected to gas chromatography linked to mass spectrometry (GC/Ms), and the amount and type compounds of the essential oils were identified. Results: The results showed that the extracted essence essential oil from the Z. clinopodioides and A. wilhelmsii has a bactericidal effect. In the obtained results by GC/Ms chromatography, in Z. clinopodioides and A. wilhelmsii essential oils, 22 and 18 compounds were identified, respectively. Conclusion: Our results showed Z. clinopodioidesand A. wilhelmsii have considered in herbals groups with antibacterial properties and after evaluating their effects in-vivo condition and to identify the active ingredients, as an alternative to synthetic drugs that commonly used to treat infections are used

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