Author(s): Aqsa Iqbal, Nicole Stahl, Erin M Davis
Introduction:
Immunoglobulin A vasculitis (formerly known as Henoch Schonlein Purpura)
is the most common pediatric vasculitis, which occurs typically at the age of 3-15 years.
Mononucleosis, group
A Streptococcus, Campylobacter and Mycoplasma are some of the common
infectious causes of immunoglobulin A vasculitis. Immunoglobulin A vasculitis is a clinically
diagnosed disease. Most common clinical features include nonthrombocytopenic nonpruritic
palpable purpura, gastrointestinal involvement, arthritis or arthralgia and renal involvement.
Biopsy of skin and/or gastrointestinal lesions confirm the diagnosis, although this is not
necessary. Immunoglobulin A vasculitis is a self-limiting disease, which resolves spontaneously.
Steroids can be used for the treatment of moderate to severe disease and for the prevention of
renal complications. Prognosis relies upon various factors among which involvement of kidneys
dictates poor prognosis and requires close follow up.
Case Presentation:
We are presenting
a case of immunoglobulin A vasculitis in a 39-year-old German male following influenza
virus infection. The infectious agent that cause immunoglobulin A vasculitis in our patient
was Influenza A virus. Biopsy of the skin lesion confirmed the diagnosis of immunoglobulin A
vasculitis in our patient. The patient responded to steroids and his skin and GI findings resolved.
Conclusion:
Our case report adds to the literature of medicine by describing influenza virus as
a cause of immunoglobulin A vasculitis in young adult patients. Considering immunoglobulin
A vasculitis after influenza and outside of the typical age of 3-15 years, can help to make earlier
diagnosis and prevent complications.